JIB-04
CAS No. 199596-05-9
JIB-04 ( JHDM Inhibitor VII;NSC 693627 )
Catalog No. M13115 CAS No. 199596-05-9
JIB-04 is a pan-selective Jumonji histone demethylase inhibitor.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 39 | In Stock |
|
10MG | 61 | In Stock |
|
25MG | 82 | In Stock |
|
50MG | 149 | In Stock |
|
100MG | 259 | In Stock |
|
200MG | 426 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameJIB-04
-
NoteResearch use only, not for human use.
-
Brief DescriptionJIB-04 is a pan-selective Jumonji histone demethylase inhibitor.
-
DescriptionJIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D in cell-free assays, respectively.
-
SynonymsJHDM Inhibitor VII;NSC 693627
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorJMJD2A; JMJD2B; JMJD2D; JMJD2E; JARID1A
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number199596-05-9
-
Formula Weight308.76
-
Molecular FormulaC17H13ClN4
-
Purity>98%(HPLC)
-
SolubilityDMSO: 25 mg/mL warmed (80.96 mM)
-
SMILESClC1=CN=C(N/N=C(C2=CC=CC=C2)/C3=NC=CC=C3)C=C1
-
Chemical Name(E)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wang, L., et al. Nat Commun, 2013. 4: p. 2035.
molnova catalog
related products
-
FB23-2
FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO.
-
RN-1 dihydrochloride
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).
-
GSK J4 hydrochloride
GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM.